Acetylaconitine is a diterpenoid alkaloid that is extracted from the roots of aconite plants. It has been used as a medicine for centuries in China and Japan. Acetylaconitine has shown anti-inflammatory properties and has been used clinically to treat inflammatory diseases, such as cancer and arthritis. Acetylaconitine binds to fatty acids, which may be due to its unsaturated alkyl chain. Acetylaconitine also blocks the action of calcium ions on cells, preventing them from releasing histamine. This drug also blocks the synthesis of prostaglandins by inhibiting cyclooxygenase activity in the cell membrane. Acetylaconitine is toxic to humans and animals because it inhibits respiration by blocking cellular respiration at mitochondria level.
Aci-Dihydroergocryptine is a reference standard for the detection of HPLC standards. It is a natural product derived from plants and has been shown to have bioactive properties. The chemical structure of Aci-Dihydroergocryptine was elucidated by spectroscopic data, which showed that it is an aglycone with a dihydroergocryptine moiety. The purity of this compound is 99% and it has been isolated from the plant Acacia catechu L. (Benth).
Adouetine Y is an anti-inflammatory agent that is used to treat allergic rhinitis. It has been shown to have a potent anti-inflammatory effect, which may be due to its ability to inhibit the production of prostaglandins. Adouetine Y is extracted from natural sources and has been shown to be effective in treating allergic rhinitis.
Angeliticin A is a natural product that has been shown to protect against reperfusion injury. It inhibits the production of reactive oxygen species and lipid peroxidation, which are the main causes of reperfusion injury. Angeliticin A also protects against ischemia by inhibiting LDL cholesterol oxidation, which reduces the risk of atherosclerosis and coronary heart disease. This compound also has been shown to inhibit HMG-CoA reductase, an enzyme involved in cholesterol synthesis, suggesting it may be useful as a treatment for hypercholesterolemia.
Atropine sulfate is a cholinergic drug that inhibits the enzyme acetylcholinesterase. It is used to treat bradycardia and to reduce the spasms of smooth muscle, including those of the bronchi, gastrointestinal tract, uterus, bladder and urinary passages. Atropine sulfate also has been used as an antidote for poisoning by organophosphates and other cholinesterase inhibitors. The drug is readily absorbed from the gastrointestinal tract, with peak plasma concentrations occurring about one hour after ingestion. The half-life is about three hours. The major route of elimination is via renal excretion of unchanged drug in urine. Atropine sulfate has a number of biological properties that make it suitable for use as a model system for studies on the effects of drugs on central nervous system function. These include its ability to cross the blood-brain barrier and inhibit acetylcholinesterase in the brain at doses lower than those required in peripheral tissues