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Acetylaconitine

Acetylaconitine is a diterpenoid alkaloid that is extracted from the roots of aconite plants. It has been used as a medicine for centuries in China and Japan. Acetylaconitine has shown anti-inflammatory properties and has been used clinically to treat inflammatory diseases, such as cancer and arthritis. Acetylaconitine binds to fatty acids, which may be due to its unsaturated alkyl chain. Acetylaconitine also blocks the action of calcium ions on cells, preventing them from releasing histamine. This drug also blocks the synthesis of prostaglandins by inhibiting cyclooxygenase activity in the cell membrane. Acetylaconitine is toxic to humans and animals because it inhibits respiration by blocking cellular respiration at mitochondria level.

Technical Data

CAS No
[77181-26-1]
Product Code
FA74131
MDL No
MFCD01673466
MOL file
Chemical Formula
C36H49NO12
Molecular Weight
687.77 g/mol
Smiles
CCN1C[C@@]2([C@@H](C[C@@H]([C@@]34[C@@H]2[C@H]([C@@H](C31)[C@@]5([C@@H]6[C@H]4C[C@@]([C@@H]6OC(=O)C7=CC=CC=C7)([C@H]([C@@H]5O)OC)O)OC(=O)C)OC)OC)OC(=O)C)COC
Storage
store at 10°C - 25°C, close container well
UN Number
UN1544
Pack Group
I
Class
6.1
GHS Information
GHS Code GHS06
Harmonized Tariff Codes
Switzerland: 29397900 - USA: 2939790000 - Slovakia: 2939799090 - UK: 2939490000 - China: 2939799099