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Benzoylhypaconine

Benzoylhypaconine is a chemical inhibitor that inhibits the enzyme alpha-ketoglutarate dehydrogenase in the electron transport chain and causes depletion of cellular energy. It has been shown to be effective against infectious diseases such as HIV, influenza, and tuberculosis. Benzoylhypaconine has also been shown to be toxic in animal studies, and is known to inhibit DNA polymerase activity. This drug has also been used as an analytical method for measuring the concentration of aconine in human serum. The matrix effect on this assay can be corrected by using dextran sulfate.

Technical Data

CAS No
[63238-66-4]
Product Code
FB158533
MDL No
MFCD01673481
MOL file
Chemical Formula
C31H43NO9
Molecular Weight
573.67 g/mol
Smiles
CN1CC2(CCC(C34C2C(C(C31)C5(C6C4CC(C6OC(=O)C7=CC=CC=C7)(C(C5O)OC)O)O)OC)OC)COC
Storage
store at <-15°C, close container well
Harmonized Tariff Codes
Switzerland: 29397900 - USA: 2939790000 - Slovakia: 2939799090 - UK: 2939490000 - China: 2939799099