공지사항
Long-lasting & non-toxic cytokine fusion proteins from Chimerigen
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AdipoGen E-News | September 2013 Special
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Cytokines & Immune Checkpoint Regulators
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Chimerigen offers a variety of non-lytic immunoglobulin-based chimeric cytokine fusion proteins, which possess both the biological functions of the cytokine moiety and a prolonged circulating half-life resul-ting from the Fc domain. |
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Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).
| IL-2 (human):Fc (human) (rec.) (non-lytic) BULK available! | CHI-HF-22002 |
50 쨉g 3 x 50 쨉g |
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| IL-2 (mouse):Fc (mouse) (rec.) (non-lytic) BULK available! | CHI-MF-12002 |
10 쨉g 5 x 10 쨉g |
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| IL-4 (human):Fc (human) (rec.) (non-lytic) BULK available! | CHI-HF-22004 |
10 쨉g 5 x 10 쨉g |
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| IL-4 (mouse):Fc (mouse) (rec.) (non-lytic) BULK available! | CHI-MF-12004 |
10 쨉g 5 x 10 쨉g |
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| IL-6 (human):Fc (human) (rec.) (non-lytic) BULK available! | CHI-HF-22006 |
50 쨉g 3 x 50 쨉g |
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| IL-6 (mouse):Fc (mouse) (rec.) (non-lytic) BULK available! | CHI-MF-12006 |
50 쨉g 3 x 50 쨉g |
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| IL-10 (human):Fc (human) (rec.) (non-lytic) BULK available! | CHI-HF-22010 |
10 쨉g 5 x 10 쨉g |
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| IL-10 (mouse):Fc (mouse) (rec.) (non-lytic) BULK available! | CHI-MF-12010 |
10 쨉g 5 x 10 쨉g |
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| IL-35 (human):Fc (human) (rec.) | CHI-HF-21035 | 25 쨉g |
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| NEW IL-35 (mouse):Fc (human) (rec.) | CHI-MF-11135 | 5 쨉g |
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CTLA-4 [CD152]:Fc -
enhances T cell cytotoxicity against tumor cells
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CTLA-4 (human):Fc (human) (rec.) BULK available! |
CHI-HF-210A4 |
100 쨉g 500 쨉g 1 mg |
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CTLA-4 (mouse):Fc (mouse) (rec.) BULK available! |
CHI-MF-110A4 |
100 쨉g 500 쨉g 1 mg |
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| CTLA-4 (mouse):Fc (mouse) (rec.) (non-lytic) BULK available! | CHI-MF-120A4 |
100 쨉g 500 쨉g 1 mg |
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PD-1 (human):Fc (human) (rec.) BULK available! |
CHI-HF-210PD1 | 100 쨉g |
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| PD-1 (human):Fc (human) (rec.) (non-lytic) BULK available! | CHI-HF-220PD1 | 200 쨉g |
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ICOS [CD278]:Fc -
required for optimal antitumor response mediated by anti-CTLA-4 treatment
| ICOS (human):Fc (human) (rec.) | CHI-HF-210ICOS |
25 쨉g 100 쨉g |
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| ICOS (human):Fc (human) (rec.) (non-lytic) | CHI-HF-220ICOS |
25 쨉g 100 쨉g |
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| Tim-3 (human):Fc (human) (rec.) | CHI-HF-210T3 | 100 쨉g |
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| Tim-3 (mouse):Fc (human) (rec.) | CHI-MF-111T3 | 100 쨉g |
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Immune Checkpoint Ligand Proteins
| B7-H4 (human):Fc (human) (rec.) | CHI-HF-210B7H4 | 100 쨉g |
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| B7-H2 (mouse):Fc (mouse) (rec.) | CHI-MF-110B7H2 | 100 쨉g |
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| PD-L1 (human):Fc (human) (rec.) | CHI-HF-210PDL1 | 100 쨉g |
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| PD-L1 (human):Fc (human) (rec.) (non-lytic) | CHI-HF-220PDL1 | 100 쨉g |
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| PD-L1 (mouse):Fc (mouse) (rec.) | CHI-MF-110PDL1 | 100 쨉g |
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| PD-L1 (mouse):Fc (mouse) (rec.) (non-lytic) | CHI-MF-120PDL1 | 100 쨉g |
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| PD-L2 (human):Fc (human) (rec.) (non-lytic) | CHI-HF-220PDL2 | 100 쨉g |
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Chimerigen Suppl. Catalog 2013
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For Ordering please visit:
www.adipogen.com
Adipogen International |
info@adipogen.com
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