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Iron, Magnesium, Calcium: the real “precious” metals

Date 2018-09-06 Hits 2511
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08232018_Inorganic Assay Kits Assay Kit

Iron, Magnesium, Calcium: the real “precious” metals

Dear chunyangtech,

Overall, metals play numerous physiological roles in nature. Cations participate in neurological transmission, muscle contraction, osmotic pressure, bone formation, oxygen transport, energy transfer and storage, etc. Additionally, they function as  cofactors  or can be found as moieties within other important biomolecules. BioVision offers a diverse portfolio of assays measuring the concentration of cations in biological samples.

Key Features:

  • Non-radioactive, specific  assays
  • Versatile:  colorimetric/fluorometric/cell-based assays
  • Convenient:  minimal sample preparation; fast protocols (1-2 hours)
  • Cost effective:  100 assays;  High-Throughput Screening Compatible
  • Validated:  tissue/cell lysate, serum, plasma, urine

08282018

Figure:  (A)  Serum Iron and TIBC determination of serum using  K392 . Assays were performed following the kit protocol.  B.Specificity of  K545  for detection of lithium (Li+) over other common monovalent, divalent and trivalent ions (each 10 nmole/well). All other cations tested contribute ≤10% interference when normalized to the signal generated by 10 nmole lithium.

Checkout the list of assay kits for inorganic cations from BioVision

Cation Role(s) Kit No. Validated sample
Calcium Bone/teeth structure
Muscle contraction/movement
Enzyme cofactor
Blood Clotting
 		K409  (F)
K380  (C) 		Cell lysate, 
serum, 
urine
Cobalt Constituent of Cobalamin (Vitamin B12)
Enzyme cofactor
 		K505  (C) Cell lysate
Iron Blood production (red cells)
Oxygen transport: hemoglobin and myoglobin
Enzyme cofactor
Synthesis of collagen and neurotransmitters
 		K390  (C) Cell lysate
TIBC Total Iron-Binding Capacity: 
blood’s ability to bind iron to transferrin
 		K392  (C) Serum, 
plasma
Lithium Does not participate in physiological processes
Used to treat mania/depression/bipolar disorder
 		K545  (C) Serum, 
plasma
Magnesium Bone structure
Enzyme cofactor
Nerve and muscle function
Participates in potassium and calcium metabolism
 		K385  (C) Tissue lysate,
Cell lysate
Nickel Enzyme cofactor
Essential nutrient for gut bacteria (prebiotic)
 		K510  (C) Tissue lysate,
Cell lysate
Sodium Maintenance of body normal body fluid levels
Nerve and muscle function
Cellular osmotic pressure
 		K391  (C) Serum, 
Urine, 
Saliva
Zinc Enzyme cofactor
Biosynthesis of DNA and RNA
 		K428  (F)
K387  (C)
K525  (F) 		Cell/tissue lysate
Biological fluids
 Cell lines

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